Frieden, MD, MPH said, "This case is a wake-up call. In this patient's case, onset of AIDS appears to have occurred within two to three months, and at most 20 months, after HIV infection. This strain also caused a rapid onset of AIDS, which usually occurs more than ten years after initial infection with HIV.
Strains of 3-DCR HIV are resistant to three of the four available types of antiviral drugs that are most commonly prescribed: nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, and protease inhibitors. While drug resistance is increasingly common among patients who have been treated for HIV, cases of 3-DCR HIV in newly-diagnosed, previously untreated patients are extremely rare, and the combination of this pattern of drug resistance and rapid progression to AIDS may not have been diagnosed previously. DOHMH is counseling and offering HIV testing to those contacts of the patient who have been identified. Since then, the patient has developed AIDS. The diagnosis of 3-DCR HIV was made shortly thereafter at the Aaron Diamond AIDS Research Center. He was first diagnosed with HIV in December 2004 and appears to have been recently infected. The patient is a male in his mid-40s who reported multiple male sex partners and unprotected anal intercourse, often while using crystal methamphetamine (crystal meth). The strain of three-class antiretroviral-resistant HIV - or 3-DCR HIV - does not respond to three classes of anti-retroviral medication, and also appears to greatly shorten the interval between HIV infection and the onset of AIDS. NEW YORK CITY - FebruA highly resistant strain of rapidly progressive human immunodeficiency virus (HIV) has been diagnosed for the first time in a New York City resident who had not previously undergone antiviral drug treatment, according to the Department of Health and Mental Hygiene (DOHMH).
Urges At-Risk Groups To Stop Risky Sexual Behavior Patients Who Are On Treatment For HIV/AIDS And Are Doing Well Do Not Need Susceptibility Testing Unless Advised By Their Physician Highly Virulent Strain Resistant to Three Types of HIV Drugs Is Rare In Patients Not Previously Treated for HIV Strain Is Also Associated with Rapid Onset of AIDS NEW YORK CITY RESIDENT DIAGNOSED WITH RARE STRAIN OF MULTI-DRUG RESISTANT HIV THAT RAPIDLY PROGRESSES TO AIDS
0 kommentar(er)
